Save your data with knoppix and erase the systemdrive.Then reinstall the OS again.Al other option are unsecure and have a high risk,that maleware surive.
Do you have any clue what virus it is, and do you have a real antivirus program that found it (if not download avira at www.avira.com).
Sometimes virusses cannot be erased and in that case it is a better option to make a backup of all your important data. You don't have to do that with knoppix, you can also just copy them to cd/dvd or whatever option you like most.
Don't forget to install a good virusscanner on your computer (after reinstalling)!
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